Thanks to the pioneering studies of Østerud and co-workers, it is now increasingly understood that natural polyphenols present in marine oils play an essential role in protecting omega-3 lipids from oxidation and autoxidation, ensuring that no proinflammatory products are formed after intake as often happens with assumption of refined omega-3 concentrates. Strong antioxidants exerting multiple biological functions, olive biophenols are ideally suited to functionalize marine oils, creating a synergy that has the potential to improve public health across the world. This study identifies suitable avenues for advancing the sustainable production of health-beneficial formulations based on newly obtained natural marine oils and olive phenolic extracts. Important educational outcomes conclude the study.